Microstructural changes in patients with progressive supranuclear palsy: A diffusion tensor imaging study
Identifieur interne : 000646 ( Main/Exploration ); précédent : 000645; suivant : 000647Microstructural changes in patients with progressive supranuclear palsy: A diffusion tensor imaging study
Auteurs : Jiunjie Wang [Taïwan] ; Yauyau Wai [Taïwan] ; Wey-Yil Lin [Taïwan] ; Shuhang Ng [Taïwan] ; Chi-Hong Wang [Taïwan] ; Renhsiang Hsieh [Taïwan] ; Chunghuang Hsieh [Taïwan] ; Rou-Shayn Chen [Taïwan] ; Chin-Song Lu [Taïwan]Source :
- Journal of Magnetic Resonance Imaging [ 1053-1807 ] ; 2010-07.
English descriptors
Abstract
Purpose:: To determine whether progressive supranuclear palsy (PSP) is associated with specific diffusion tensor imaging (DTI) patterns of diffusivity, anisotropy, and coherence in functionally relevant brain areas. Materials and Methods:: In all, 17 PSP patients and 17 controls were scanned using a 3 T magnetic resonance imaging (MRI) scanner. Patients were assessed in the off‐medication condition using the Hoehn and Yahr staging and the United Parkinson's Disease Rating Scale, motor subscale (UPDRS‐III). Diffusion information were analyzed in relation to disease severity and subtypes. Results:: Numerous changes in diffusion properties were identified in the subcortical areas. In the midbrain, fractional anisotropy (FA) decreased and MD (mean diffusivity) increased with disease progression. UPDRS‐III scores correlated positively with both FA in the caudate and MD in the pons. DTI analysis of disease subtypes demonstrated significant differences between PSP‐Parkinsonism and Steele‐Richardson‐Olszewski syndrome in axial diffusivity values in the putamen and globus pallidus, as well as in intervoxel diffusion coherence values in the middle cerebellar peduncle. Conclusion:: Our findings, cautiously interpreted, demonstrate the advantage of using a functional imaging technique to aid in the specificity of defining more precisely the pathological processes taking place in white and gray matter regions in PSP. J. Magn. Reson. Imaging 2010;32:69–75. © 2010 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/jmri.22229
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Microstructural changes in patients with progressive supranuclear palsy: A diffusion tensor imaging study</title><author><name sortKey="Wang, Jiunjie" sort="Wang, Jiunjie" uniqKey="Wang J" first="Jiunjie" last="Wang">Jiunjie Wang</name></author><author><name sortKey="Wai, Yauyau" sort="Wai, Yauyau" uniqKey="Wai Y" first="Yauyau" last="Wai">Yauyau Wai</name></author><author><name sortKey="Lin, Wey Il" sort="Lin, Wey Il" uniqKey="Lin W" first="Wey-Yil" last="Lin">Wey-Yil Lin</name></author><author><name sortKey="Ng, Shuhang" sort="Ng, Shuhang" uniqKey="Ng S" first="Shuhang" last="Ng">Shuhang Ng</name></author><author><name sortKey="Wang, Chi Ong" sort="Wang, Chi Ong" uniqKey="Wang C" first="Chi-Hong" last="Wang">Chi-Hong Wang</name></author><author><name sortKey="Hsieh, Renhsiang" sort="Hsieh, Renhsiang" uniqKey="Hsieh R" first="Renhsiang" last="Hsieh">Renhsiang Hsieh</name></author><author><name sortKey="Hsieh, Chunghuang" sort="Hsieh, Chunghuang" uniqKey="Hsieh C" first="Chunghuang" last="Hsieh">Chunghuang Hsieh</name></author><author><name sortKey="Chen, Rou Hayn" sort="Chen, Rou Hayn" uniqKey="Chen R" first="Rou-Shayn" last="Chen">Rou-Shayn Chen</name></author><author><name sortKey="Lu, Chin Ong" sort="Lu, Chin Ong" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:8FBD05D1AD6BB8E4C892033FB8D59CA95D3727D9</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/jmri.22229</idno><idno type="url">https://api.istex.fr/document/8FBD05D1AD6BB8E4C892033FB8D59CA95D3727D9/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001E21</idno><idno type="wicri:Area/Main/Curation">001B35</idno><idno type="wicri:Area/Main/Exploration">000646</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Microstructural changes in patients with progressive supranuclear palsy: A diffusion tensor imaging study</title><author><name sortKey="Wang, Jiunjie" sort="Wang, Jiunjie" uniqKey="Wang J" first="Jiunjie" last="Wang">Jiunjie Wang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Radiological Sciences, Chang Gung University</wicri:regionArea><wicri:noRegion>Chang Gung University</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Molecular Imaging Centre, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Wai, Yauyau" sort="Wai, Yauyau" uniqKey="Wai Y" first="Yauyau" last="Wai">Yauyau Wai</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Radiological Sciences, Chang Gung University</wicri:regionArea><wicri:noRegion>Chang Gung University</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Molecular Imaging Centre, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Wey Il" sort="Lin, Wey Il" uniqKey="Lin W" first="Wey-Yil" last="Lin">Wey-Yil Lin</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Ng, Shuhang" sort="Ng, Shuhang" uniqKey="Ng S" first="Shuhang" last="Ng">Shuhang Ng</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Radiological Sciences, Chang Gung University</wicri:regionArea><wicri:noRegion>Chang Gung University</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Molecular Imaging Centre, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Chi Ong" sort="Wang, Chi Ong" uniqKey="Wang C" first="Chi-Hong" last="Wang">Chi-Hong Wang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Cardinal Tien Hospital, Yung‐Ho Branch</wicri:regionArea><wicri:noRegion>Yung‐Ho Branch</wicri:noRegion></affiliation></author><author><name sortKey="Hsieh, Renhsiang" sort="Hsieh, Renhsiang" uniqKey="Hsieh R" first="Renhsiang" last="Hsieh">Renhsiang Hsieh</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Radiological Sciences, Chang Gung University</wicri:regionArea><wicri:noRegion>Chang Gung University</wicri:noRegion></affiliation></author><author><name sortKey="Hsieh, Chunghuang" sort="Hsieh, Chunghuang" uniqKey="Hsieh C" first="Chunghuang" last="Hsieh">Chunghuang Hsieh</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Rou Hayn" sort="Chen, Rou Hayn" uniqKey="Chen R" first="Rou-Shayn" last="Chen">Rou-Shayn Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Chin Ong" sort="Lu, Chin Ong" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Chang Gung Memorial Hospital</wicri:regionArea><wicri:noRegion>Chang Gung Memorial Hospital</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Magnetic Resonance Imaging</title><title level="j" type="abbrev">J. Magn. Reson. Imaging</title><idno type="ISSN">1053-1807</idno><idno type="eISSN">1522-2586</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-07">2010-07</date><biblScope unit="volume">32</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="69">69</biblScope><biblScope unit="page" to="75">75</biblScope></imprint><idno type="ISSN">1053-1807</idno></series><idno type="istex">8FBD05D1AD6BB8E4C892033FB8D59CA95D3727D9</idno><idno type="DOI">10.1002/jmri.22229</idno><idno type="ArticleID">JMRI22229</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1053-1807</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>basal ganglia</term><term>diffusion tensor imaging</term><term>progressive supranuclear palsy</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Purpose:: To determine whether progressive supranuclear palsy (PSP) is associated with specific diffusion tensor imaging (DTI) patterns of diffusivity, anisotropy, and coherence in functionally relevant brain areas. Materials and Methods:: In all, 17 PSP patients and 17 controls were scanned using a 3 T magnetic resonance imaging (MRI) scanner. Patients were assessed in the off‐medication condition using the Hoehn and Yahr staging and the United Parkinson's Disease Rating Scale, motor subscale (UPDRS‐III). Diffusion information were analyzed in relation to disease severity and subtypes. Results:: Numerous changes in diffusion properties were identified in the subcortical areas. In the midbrain, fractional anisotropy (FA) decreased and MD (mean diffusivity) increased with disease progression. UPDRS‐III scores correlated positively with both FA in the caudate and MD in the pons. DTI analysis of disease subtypes demonstrated significant differences between PSP‐Parkinsonism and Steele‐Richardson‐Olszewski syndrome in axial diffusivity values in the putamen and globus pallidus, as well as in intervoxel diffusion coherence values in the middle cerebellar peduncle. Conclusion:: Our findings, cautiously interpreted, demonstrate the advantage of using a functional imaging technique to aid in the specificity of defining more precisely the pathological processes taking place in white and gray matter regions in PSP. J. Magn. Reson. Imaging 2010;32:69–75. © 2010 Wiley‐Liss, Inc.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Wang, Jiunjie" sort="Wang, Jiunjie" uniqKey="Wang J" first="Jiunjie" last="Wang">Jiunjie Wang</name></noRegion><name sortKey="Chen, Rou Hayn" sort="Chen, Rou Hayn" uniqKey="Chen R" first="Rou-Shayn" last="Chen">Rou-Shayn Chen</name><name sortKey="Hsieh, Chunghuang" sort="Hsieh, Chunghuang" uniqKey="Hsieh C" first="Chunghuang" last="Hsieh">Chunghuang Hsieh</name><name sortKey="Hsieh, Renhsiang" sort="Hsieh, Renhsiang" uniqKey="Hsieh R" first="Renhsiang" last="Hsieh">Renhsiang Hsieh</name><name sortKey="Lin, Wey Il" sort="Lin, Wey Il" uniqKey="Lin W" first="Wey-Yil" last="Lin">Wey-Yil Lin</name><name sortKey="Lu, Chin Ong" sort="Lu, Chin Ong" uniqKey="Lu C" first="Chin-Song" last="Lu">Chin-Song Lu</name><name sortKey="Ng, Shuhang" sort="Ng, Shuhang" uniqKey="Ng S" first="Shuhang" last="Ng">Shuhang Ng</name><name sortKey="Ng, Shuhang" sort="Ng, Shuhang" uniqKey="Ng S" first="Shuhang" last="Ng">Shuhang Ng</name><name sortKey="Ng, Shuhang" sort="Ng, Shuhang" uniqKey="Ng S" first="Shuhang" last="Ng">Shuhang Ng</name><name sortKey="Wai, Yauyau" sort="Wai, Yauyau" uniqKey="Wai Y" first="Yauyau" last="Wai">Yauyau Wai</name><name sortKey="Wai, Yauyau" sort="Wai, Yauyau" uniqKey="Wai Y" first="Yauyau" last="Wai">Yauyau Wai</name><name sortKey="Wai, Yauyau" sort="Wai, Yauyau" uniqKey="Wai Y" first="Yauyau" last="Wai">Yauyau Wai</name><name sortKey="Wang, Chi Ong" sort="Wang, Chi Ong" uniqKey="Wang C" first="Chi-Hong" last="Wang">Chi-Hong Wang</name><name sortKey="Wang, Jiunjie" sort="Wang, Jiunjie" uniqKey="Wang J" first="Jiunjie" last="Wang">Jiunjie Wang</name><name sortKey="Wang, Jiunjie" sort="Wang, Jiunjie" uniqKey="Wang J" first="Jiunjie" last="Wang">Jiunjie Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000646 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000646 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:8FBD05D1AD6BB8E4C892033FB8D59CA95D3727D9
|texte= Microstructural changes in patients with progressive supranuclear palsy: A diffusion tensor imaging study
}}
| This area was generated with Dilib version V0.6.23. |  |